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Doctaine Cream

Lidocaine and prilocaine cream, applied to intact skin under occlusive dressing, provides dermal analgesia by the release of lidocaine and prilocaine from the cream into the epidermal and dermal layers of the skin and by the accumulation of lidocaine and prilocaine in the vicinity of dermal pain receptors and nerve endings. Lidocaine and prilocaine are amide-type local anesthetic agents.


Each gram contains:

Lidocaine USP 25 mg

Prilocaine USP 25 mg

In water-Miscible base.


Topical anaesthetic for use on

  • Normal intact skin for local analgesia.
  • Genital mucous membranes for superficial minor surgery and as pretreatment for infiltration anaesthesia


Adult Patients-Intact Skin A thick layer of lidocaine and prilocaine cream is applied to intact skin and covered with an occlusive dressing. Minor Dermal Procedures: For minor procedures such as intravenous cannulation and venipuncture, apply 2.5 grams of lidocaine and 2 prilocaine cream, over 20 to 25 cm of skin surface for at least 1 hour. Major Dermal Procedures: For more painful dermatological procedures involving a larger skin area such as split thickness skin graft harvesting, apply 2 grams of lidocaine and prilocaine cream, per 2 10 cm of skin and allow remaining in contact with the skin for at least 2 hours.

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